On September 10, 2013, Dr. Maria Vosjan of BV Cyclotron VU was a guest speaker at the Webinar Advancing Discovery and Development of Biologics Through Non-Invasive Biodistribution Imaging, hosted by Molecular Imaging, Inc..
See the Brainshark Powerpoint presentation
Non-invasive, translational imaging has been playing an increasingly important role in the discovery and development of new biologic and pharmaceutical molecules. In this context, the webinar delved into the concepts and practical benefits of the dual labeling and imaging strategy, including an overview of the key imaging technologies (PET and SPECT) and how they compare and complement. Case study examples were also discussed, as well as an overview of the key challenges and relevant opportunities to utilize this fast-growing technology. Discussion of how these strategies can be quickly implemented, without substantial capital investment, were also included.
Dr. Maria Vosjan presented an overview of immuno-PET imaging, with a focus on detection and imaging of antibodies in animal models and human patients based on 89Zr and 124I. The use, production and radiochemistry challenges were compared for each isotope, and preclinical and clinical immuno-PET imaging examples were given which that demonstrate the utility of these approaches.